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5eua

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Current revision (08:24, 12 July 2023) (edit) (undo)
 
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==Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam==
==Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam==
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<StructureSection load='5eua' size='340' side='right' caption='[[5eua]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='5eua' size='340' side='right'caption='[[5eua]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxh 4mxh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EUA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxh 4mxh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EUA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eoe|5eoe]], [[5eoo|5eoo]], [[5eph|5eph]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla(BEL1), blaBEL-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [https://pdbe.org/5eua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [https://www.ebi.ac.uk/pdbsum/5eua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [http://pdbe.org/5eua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [http://www.ebi.ac.uk/pdbsum/5eua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q3SAW3_PSEAI Q3SAW3_PSEAI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Benvenuti, M]]
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[[Category: Docquier, J D]]
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[[Category: Luca, F De]]
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[[Category: Mangani, S]]
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[[Category: Pozzi, C]]
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[[Category: Extended-spectrum beta-lactamase]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Oxacephem antibiotic]]
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Benvenuti M]]
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[[Category: De Luca F]]
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[[Category: Docquier JD]]
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[[Category: Mangani S]]
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[[Category: Pozzi C]]

Current revision

Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam

PDB ID 5eua

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