5f53

<table><tr><td colspan='2'>[[5f53]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F53 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F53 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zcn|4zcn]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f53 OCA], [http://pdbe.org/5f53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f53 RCSB], [http://www.ebi.ac.uk/pdbsum/5f53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f53 ProSAT]</span></td></tr>

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== Publication Abstract from PubMed ==

We have engineered a metal-binding site into the novel artificial beta-propeller protein Pizza. This new Pizza variant carries two nearly identical domains per polypeptide chain, and forms a trimer with three-fold symmetry. The designed single metal ion binding site lies on the symmetry axis, bonding the trimer together. Two copies of the trimer associate in the presence of cadmium chloride in solution, and very high-resolution X-ray crystallographic analysis reveals a nanocrystal of cadmium chloride, sandwiched between two trimers of the protein. This nanocrystal, containing seven cadmium ions lying in a plane and twelve interspersed chloride ions, is the smallest reported to date. Our results indicate the feasibility of using rationally designed symmetrical proteins to biomineralize nanocrystals with useful properties.

Biomineralization of a Cadmium Chloride Nanocrystal by a Designed Symmetrical Protein.,Voet AR, Noguchi H, Addy C, Zhang KY, Tame JR Angew Chem Int Ed Engl. 2015 Jul 1. doi: 10.1002/anie.201503575. PMID:26136355<ref>PMID:26136355</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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<div class="pdbe-citations 5f53" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Tame, J R.H]]

[[Category: Voet, A R.D]]

[[Category: Computational protein design]]

[[Category: Self-assembly]]