1lk9

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[[Image:1lk9.gif|left|200px]]
[[Image:1lk9.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1lk9 |SIZE=350|CAPTION= <scene name='initialview01'>1lk9</scene>, resolution 1.53&Aring;
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The line below this paragraph, containing "STRUCTURE_1lk9", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5&#39;-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Alliin_lyase Alliin lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.4 4.4.1.4] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1lk9| PDB=1lk9 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lk9 OCA], [http://www.ebi.ac.uk/pdbsum/1lk9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1lk9 RCSB]</span>
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}}
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'''The Three-dimensional Structure of Alliinase from Garlic'''
'''The Three-dimensional Structure of Alliinase from Garlic'''
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[[Category: Kuettner, E B.]]
[[Category: Kuettner, E B.]]
[[Category: Weiss, M S.]]
[[Category: Weiss, M S.]]
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[[Category: chloride binding]]
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[[Category: Chloride binding]]
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[[Category: egf-like domain]]
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[[Category: Egf-like domain]]
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[[Category: plp type 1]]
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[[Category: Plp type 1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:00:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:03:46 2008''
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Revision as of 21:00, 2 May 2008

Template:STRUCTURE 1lk9

The Three-dimensional Structure of Alliinase from Garlic


Overview

Despite the fact that many cultures around the world value and utilize garlic as a fundamental component of their cuisine as well as of their medicine cabinets, relatively little is known about the plant's protein configuration that is responsible for the specific properties of garlic. Here, we report the three-dimensional structure of the garlic enzyme alliinase at 1.5 A resolution. Alliinase constitutes the major protein component in garlic bulbs, and it is able to cleave carbon-sulfur bonds. The active enzyme is a pyridoxal-5'-phosphate-dependent homodimeric glycoprotein and belongs to the class I family of pyridoxal-5'-phosphate-dependent enzymes. In addition, it contains a novel epidermal growth factor-like domain that makes it unique among all pyridoxal-5'-phosphate-dependent enzymes.

About this Structure

1LK9 is a Single protein structure of sequence from Allium sativum. Full crystallographic information is available from OCA.

Reference

The active principle of garlic at atomic resolution., Kuettner EB, Hilgenfeld R, Weiss MS, J Biol Chem. 2002 Nov 29;277(48):46402-7. Epub 2002 Sep 15. PMID:12235163 Page seeded by OCA on Sat May 3 00:00:00 2008

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