6z6q
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-ethyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser)== |
| - | <StructureSection load='6z6q' size='340' side='right'caption='[[6z6q]]' scene=''> | + | <StructureSection load='6z6q' size='340' side='right'caption='[[6z6q]], [[Resolution|resolution]] 1.81Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6z6q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z6Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Z6Q FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z6q OCA], [https://pdbe.org/6z6q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z6q RCSB], [https://www.ebi.ac.uk/pdbsum/6z6q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z6q ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=QA8:(3~{R})-3-ethyl-2-oxidanylidene-pentanedioic+acid'>QA8</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z6q OCA], [https://pdbe.org/6z6q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z6q RCSB], [https://www.ebi.ac.uk/pdbsum/6z6q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z6q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ASPH_HUMAN ASPH_HUMAN] Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.<ref>PMID:22586105</ref> Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.<ref>PMID:22586105</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Hydroxylases 3D structures|Hydroxylases 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Brewitz L]] |
| + | [[Category: Nakashima Y]] | ||
| + | [[Category: Schofield CJ]] | ||
Revision as of 06:17, 19 July 2023
Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-ethyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser)
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