5fdp
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution.== | ==Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution.== | ||
| - | <StructureSection load='5fdp' size='340' side='right' caption='[[5fdp]], [[Resolution|resolution]] 2.25Å' scene=''> | + | <StructureSection load='5fdp' size='340' side='right'caption='[[5fdp]], [[Resolution|resolution]] 2.25Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5fdp]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5fdp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FDP FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5WR:(4~{S})-4-METHYL-~{N}-[3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-5-(TRIFLUOROMETHYL)PHENYL]-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLINE-7-CARBOXAMIDE'>5WR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5WR:(4~{S})-4-METHYL-~{N}-[3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-5-(TRIFLUOROMETHYL)PHENYL]-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLINE-7-CARBOXAMIDE'>5WR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdp OCA], [https://pdbe.org/5fdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fdp RCSB], [https://www.ebi.ac.uk/pdbsum/5fdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdp ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DDR1_HUMAN DDR1_HUMAN] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 18: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 5fdp" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5fdp" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Epithelial discoidin domain-containing receptor|Epithelial discoidin domain-containing receptor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bartual | + | [[Category: Bartual SG]] |
| - | [[Category: Borkowska | + | [[Category: Borkowska O]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Bullock | + | [[Category: Bullock A]] |
| - | [[Category: Burgess-Brown | + | [[Category: Burgess-Brown N]] |
| - | [[Category: Chaikuad | + | [[Category: Chaikuad A]] |
| - | + | [[Category: Ding K]] | |
| - | [[Category: Ding | + | [[Category: Edwards AM]] |
| - | [[Category: Edwards | + | [[Category: Kopec J]] |
| - | [[Category: Kopec | + | [[Category: Kupinska K]] |
| - | [[Category: Kupinska | + | [[Category: Mahajan P]] |
| - | [[Category: Mahajan | + | [[Category: Mukhopadhyay S]] |
| - | [[Category: Mukhopadhyay | + | [[Category: Newman J]] |
| - | [[Category: Newman | + | [[Category: Pinkas DM]] |
| - | [[Category: Pinkas | + | [[Category: Sorell F]] |
| - | + | [[Category: Strain-Damerell C]] | |
| - | [[Category: Sorell | + | [[Category: Tallant C]] |
| - | [[Category: Strain-Damerell | + | [[Category: Talon R]] |
| - | [[Category: Tallant | + | [[Category: Wang Z]] |
| - | [[Category: Talon | + | [[Category: Williams E]] |
| - | [[Category: Wang | + | [[Category: Von Delft F]] |
| - | [[Category: Williams | + | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution.
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bartual SG | Borkowska O | Bountra C | Bullock A | Burgess-Brown N | Chaikuad A | Ding K | Edwards AM | Kopec J | Kupinska K | Mahajan P | Mukhopadhyay S | Newman J | Pinkas DM | Sorell F | Strain-Damerell C | Tallant C | Talon R | Wang Z | Williams E | Von Delft F
