7yhn
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN== | |
| - | + | <StructureSection load='7yhn' size='340' side='right'caption='[[7yhn]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7yhn]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YHN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=IUK:4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide'>IUK</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yhn OCA], [https://pdbe.org/7yhn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yhn RCSB], [https://www.ebi.ac.uk/pdbsum/7yhn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yhn ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Lin | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Sus scrofa]] |
| - | [[Category: | + | [[Category: Chen X]] |
| - | [[Category: Zhang | + | [[Category: Du T]] |
| + | [[Category: Hou Z]] | ||
| + | [[Category: Ji M]] | ||
| + | [[Category: Lin S]] | ||
| + | [[Category: Lu D]] | ||
| + | [[Category: Wu D]] | ||
| + | [[Category: Xu H]] | ||
| + | [[Category: Zhang J]] | ||
| + | [[Category: Zhang K]] | ||
Revision as of 12:34, 26 July 2023
ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN
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Categories: Large Structures | Sus scrofa | Chen X | Du T | Hou Z | Ji M | Lin S | Lu D | Wu D | Xu H | Zhang J | Zhang K
