7ype
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of AsfvPCNA in space group of P63== | |
| - | + | <StructureSection load='7ype' size='340' side='right'caption='[[7ype]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7ype]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/African_swine_fever_virus African swine fever virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YPE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ype FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ype OCA], [https://pdbe.org/7ype PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ype RCSB], [https://www.ebi.ac.uk/pdbsum/7ype PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ype ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0A1E3R5_ASF A0A0A1E3R5_ASF] Plays a role in the inhibition of host innate immune system by acting as a negatively regulator of type I interferon production. Mechanistically, interacts with and prevents host IRF3 nuclear localization to inhibit its transcriptional activity.[ARBA:ARBA00034465] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: African swine fever virus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gan JH]] | ||
| + | [[Category: Shao ZW]] | ||
Revision as of 12:34, 26 July 2023
Crystal structure of AsfvPCNA in space group of P63
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