8ow4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==2.75 angstrom crystal structure of human NFAT1 with bound DNA== | |
| - | + | <StructureSection load='8ow4' size='340' side='right'caption='[[8ow4]], [[Resolution|resolution]] 2.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ow4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OW4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ow4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ow4 OCA], [https://pdbe.org/8ow4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ow4 RCSB], [https://www.ebi.ac.uk/pdbsum/8ow4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ow4 ProSAT]</span></td></tr> |
| - | [[Category: Erausquin | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/NFAC2_HUMAN NFAC2_HUMAN] Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.<ref>PMID:21871017</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Erausquin E]] | ||
| + | [[Category: Hernandez-Morales S]] | ||
| + | [[Category: Lasarte JJ]] | ||
| + | [[Category: Lopez-Sagaseta J]] | ||
| + | [[Category: Lozano T]] | ||
| + | [[Category: Urdiciain A]] | ||
Current revision
2.75 angstrom crystal structure of human NFAT1 with bound DNA
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