1fx1
From Proteopedia
(Difference between revisions)
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<StructureSection load='1fx1' size='340' side='right'caption='[[1fx1]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1fx1' size='340' side='right'caption='[[1fx1]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1fx1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FX1 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[1fx1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FX1 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fx1 OCA], [https://pdbe.org/1fx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fx1 RCSB], [https://www.ebi.ac.uk/pdbsum/1fx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fx1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fx1 OCA], [https://pdbe.org/1fx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fx1 RCSB], [https://www.ebi.ac.uk/pdbsum/1fx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fx1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/FLAV_DESVH FLAV_DESVH] Low-potential electron donor to a number of redox enzymes. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fx1 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fx1 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The crystal structure of the oxidized form of flavodoxin from Desulfovibrio vulgaris has been studied at 2.0-A resolution, and a detailed description of the region around the flavin mononucleotide binding site is now available. The flavin is between a tyrosine group, roughly parallel to it on one side, and a tryptophan, about 45 degrees from being parallel, on the other side. The two carbonyl groups and two nitrogen atoms of the flavin are hydrogen bonded to the peptide chain of the protein, while the two methyl groups are exposed at the surface of the protein. The phosphate group of the flavin mononucleotide is inside the protein and extensively hydrogen bonded to it. The ribityl group is hydrogen bonded both to the protein and to water on the surface of the protein. | ||
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| - | The binding of riboflavin-5'-phosphate in a flavoprotein: flavodoxin at 2.0-Angstrom resolution.,Watenpaugh KD, Sieker LC, Jensen LH Proc Natl Acad Sci U S A. 1973 Dec;70(12):3857-60. PMID:4521211<ref>PMID:4521211</ref> | ||
| - | |||
| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1fx1" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Flavodoxin 3D structures|Flavodoxin 3D structures]] | *[[Flavodoxin 3D structures|Flavodoxin 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Desulfovibrio vulgaris]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Jensen | + | [[Category: Jensen LH]] |
| - | [[Category: Sieker | + | [[Category: Sieker LC]] |
| - | [[Category: Watenpaugh | + | [[Category: Watenpaugh KD]] |
Current revision
A CRYSTALLOGRAPHIC STRUCTURAL STUDY OF THE OXIDATION STATES OF DESULFOVIBRIO VULGARIS FLAVODOXIN
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