2mv1

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==Solution NMR structure of Human Relaxin-2==
==Solution NMR structure of Human Relaxin-2==
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<StructureSection load='2mv1' size='340' side='right'caption='[[2mv1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2mv1' size='340' side='right'caption='[[2mv1]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mv1]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MV1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mv1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MV1 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6rlx|6rlx]], [[2fhw|2fhw]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mv1 OCA], [https://pdbe.org/2mv1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mv1 RCSB], [https://www.ebi.ac.uk/pdbsum/2mv1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mv1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mv1 OCA], [https://pdbe.org/2mv1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mv1 RCSB], [https://www.ebi.ac.uk/pdbsum/2mv1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mv1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/REL2_HUMAN REL2_HUMAN]] Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
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[https://www.uniprot.org/uniprot/REL2_HUMAN REL2_HUMAN] Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Haugaard-Kedstrom, L M]]
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[[Category: Haugaard-Kedstrom LM]]
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[[Category: Rosengren, K]]
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[[Category: Rosengren K]]
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[[Category: Insulin/relaxin family fold]]
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[[Category: Signaling protein]]
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[[Category: Signalling protein]]
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Revision as of 13:09, 26 July 2023

Solution NMR structure of Human Relaxin-2

PDB ID 2mv1

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