5fr3

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Current revision (13:19, 26 July 2023) (edit) (undo)
 
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<StructureSection load='5fr3' size='340' side='right'caption='[[5fr3]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
<StructureSection load='5fr3' size='340' side='right'caption='[[5fr3]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5fr3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FR3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FR3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5fr3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FR3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.935&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fr3 OCA], [http://pdbe.org/5fr3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fr3 RCSB], [http://www.ebi.ac.uk/pdbsum/5fr3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fr3 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fr3 OCA], [https://pdbe.org/5fr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fr3 RCSB], [https://www.ebi.ac.uk/pdbsum/5fr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fr3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN]] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
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[https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5fr3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5fr3" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Anthrax protective antigen 3D structures|Anthrax protective antigen 3D structures]]
 
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus anthracis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Baets, G De]]
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[[Category: Beerten J]]
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[[Category: Beerten, J]]
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[[Category: Brams M]]
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[[Category: Brams, M]]
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[[Category: De Baets G]]
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[[Category: Durme, J van]]
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[[Category: De Smet F]]
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[[Category: Gallardo, R]]
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[[Category: Gallardo R]]
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[[Category: Ganesan, A]]
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[[Category: Ganesan A]]
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[[Category: Kant, R van der]]
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[[Category: Langenberg T]]
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[[Category: Langenberg, T]]
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[[Category: Ramakers M]]
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[[Category: Ramakers, M]]
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[[Category: Rousseau F]]
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[[Category: Rousseau, F]]
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[[Category: Schymkowitz J]]
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[[Category: Schymkowitz, J]]
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[[Category: Siekierska A]]
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[[Category: Siekierska, A]]
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[[Category: Ulens C]]
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[[Category: Smet, F De]]
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[[Category: Wilkinson H]]
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[[Category: Ulens, C]]
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[[Category: Van Durme J]]
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[[Category: Wilkinson, H]]
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[[Category: Van der Kant R]]
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[[Category: Anthrax protective antigen]]
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[[Category: Toxin]]
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Current revision

X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E)

PDB ID 5fr3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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