5fwc

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Current revision (13:29, 26 July 2023) (edit) (undo)
 
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<StructureSection load='5fwc' size='340' side='right'caption='[[5fwc]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='5fwc' size='340' side='right'caption='[[5fwc]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5fwc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FWC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5fwc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FWC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fw6|5fw6]], [[5fw7|5fw7]], [[5fw8|5fw8]], [[5fw9|5fw9]], [[5fwb|5fwb]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwc OCA], [http://pdbe.org/5fwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fwc RCSB], [http://www.ebi.ac.uk/pdbsum/5fwc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwc OCA], [https://pdbe.org/5fwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fwc RCSB], [https://www.ebi.ac.uk/pdbsum/5fwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwc ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN]] West syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN]] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
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[https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
==See Also==
==See Also==
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*[[Spectrin|Spectrin]]
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*[[Spectrin 3D structures|Spectrin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gallego, P]]
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[[Category: Gallego P]]
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[[Category: Navarro, S]]
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[[Category: Navarro S]]
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[[Category: Reverter, D]]
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[[Category: Reverter D]]
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[[Category: Ventura, S]]
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[[Category: Ventura S]]
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[[Category: Spectrin sh3]]
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[[Category: Structural protein]]
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Current revision

Human Spectrin SH3 domain D48G, E7A, K60A

PDB ID 5fwc

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