8dyt
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of 227 Fab in complex with (NPNA)8 peptide== | |
| - | + | <StructureSection load='8dyt' size='340' side='right'caption='[[8dyt]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8dyt]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DYT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DYT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dyt OCA], [https://pdbe.org/8dyt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dyt RCSB], [https://www.ebi.ac.uk/pdbsum/8dyt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dyt ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Martin | + | == Function == |
| + | [https://www.uniprot.org/uniprot/Q5R2L4_PLAFA Q5R2L4_PLAFA] Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.[RuleBase:RU369056] In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.[RuleBase:RU369056] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Plasmodium falciparum 3D7]] | ||
| + | [[Category: Martin GM]] | ||
| + | [[Category: Ward AB]] | ||
Revision as of 10:37, 2 August 2023
Cryo-EM structure of 227 Fab in complex with (NPNA)8 peptide
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