This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


8t5x

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:41, 2 August 2023) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8t5x is ON HOLD until 2025-06-14
+
==Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)==
-
 
+
<StructureSection load='8t5x' size='340' side='right'caption='[[8t5x]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
-
Authors: Ferguson, J.A., Sun, X., Leach, B.I., Stanfield, R.L., Dyson, H.J., Wright, P.E.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8t5x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8T5X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8T5X FirstGlance]. <br>
-
Description: Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8t5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8t5x OCA], [https://pdbe.org/8t5x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8t5x RCSB], [https://www.ebi.ac.uk/pdbsum/8t5x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8t5x ProSAT]</span></td></tr>
-
[[Category: Stanfield, R.L]]
+
</table>
-
[[Category: Leach, B.I]]
+
== Function ==
-
[[Category: Wright, P.E]]
+
[https://www.uniprot.org/uniprot/E9KL36_HUMAN E9KL36_HUMAN] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.[ARBA:ARBA00025504][RuleBase:RU361269]
-
[[Category: Ferguson, J.A]]
+
__TOC__
-
[[Category: Dyson, H.J]]
+
</StructureSection>
-
[[Category: Sun, X]]
+
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Dyson HJ]]
 +
[[Category: Ferguson JA]]
 +
[[Category: Leach BI]]
 +
[[Category: Stanfield RL]]
 +
[[Category: Sun X]]
 +
[[Category: Wright PE]]

Current revision

Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)

PDB ID 8t5x

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools