1a4k

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='1a4k' size='340' side='right'caption='[[1a4k]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='1a4k' size='340' side='right'caption='[[1a4k]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1a4k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A4K FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1a4k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A4K FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=FRA:[4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0+2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC+ACID'>FRA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=FRA:[4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0+2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC+ACID'>FRA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4k OCA], [https://pdbe.org/1a4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a4k RCSB], [https://www.ebi.ac.uk/pdbsum/1a4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4k ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4k OCA], [https://pdbe.org/1a4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a4k RCSB], [https://www.ebi.ac.uk/pdbsum/1a4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4k ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
-
[[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN]] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[https://omim.org/entry/614102 614102]]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref>
+
[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[https://omim.org/entry/614102 614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 36: Line 39:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Mus musculus]]
-
[[Category: Romesburg, F E]]
+
[[Category: Romesburg FE]]
-
[[Category: Schultz, P G]]
+
[[Category: Schultz PG]]
-
[[Category: Spiller, B W]]
+
[[Category: Spiller BW]]
-
[[Category: Stevens, R C]]
+
[[Category: Stevens RC]]
-
[[Category: Antibody]]
+
-
[[Category: Catalytic antibody]]
+
-
[[Category: Diels alder]]
+
-
[[Category: Germline]]
+
-
[[Category: Immunoglobulin]]
+

Revision as of 10:46, 2 August 2023

DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE

PDB ID 1a4k

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1a4k"
Personal tools