1wua

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Current revision (11:25, 2 August 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUA FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AP8:(8R,9R,10R,11R,14S,18S,20S,24S)-24-{(1R,2S,3R,6R,7R,8R,9S,10E)-8-(ACETYLOXY)-6-[(N,N-DIMETHYLALANYL)OXY]-11-[FORMYL(METHYL)AMINO]-2-HYDROXY-1,3,7,9-TETRAMETHYLUNDEC-10-ENYL}-10-HYDROXY-14,20-DIMETHOXY-9,11,15,18-TETRAMETHYL-2-OXOOXACYCLOTETRACOSA-3,5,15,21-TETRAEN-8-YL+N,N,O-TRIMETHYLSERINATE'>AP8</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AP8:(8R,9R,10R,11R,14S,18S,20S,24S)-24-{(1R,2S,3R,6R,7R,8R,9S,10E)-8-(ACETYLOXY)-6-[(N,N-DIMETHYLALANYL)OXY]-11-[FORMYL(METHYL)AMINO]-2-HYDROXY-1,3,7,9-TETRAMETHYLUNDEC-10-ENYL}-10-HYDROXY-14,20-DIMETHOXY-9,11,15,18-TETRAMETHYL-2-OXOOXACYCLOTETRACOSA-3,5,15,21-TETRAEN-8-YL+N,N,O-TRIMETHYLSERINATE'>AP8</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wua OCA], [https://pdbe.org/1wua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wua RCSB], [https://www.ebi.ac.uk/pdbsum/1wua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wua ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wua OCA], [https://pdbe.org/1wua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wua RCSB], [https://www.ebi.ac.uk/pdbsum/1wua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wua ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Hirata, K]]
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[[Category: Hirata K]]
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[[Category: Kato, K]]
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[[Category: Kato K]]
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[[Category: Kigoshi, H]]
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[[Category: Kigoshi H]]
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[[Category: Kuroda, T]]
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[[Category: Kuroda T]]
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[[Category: Muraoka, S]]
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[[Category: Muraoka S]]
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[[Category: Suenaga, K]]
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[[Category: Suenaga K]]
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[[Category: Takata, M]]
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[[Category: Takata M]]
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[[Category: Tanaka, H]]
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[[Category: Tanaka H]]
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[[Category: Yamada, K]]
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[[Category: Yamada K]]
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[[Category: Yamamoto, M]]
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[[Category: Yamamoto M]]
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[[Category: Aplyronine some]]
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[[Category: Macrolide]]
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[[Category: Marine sponge]]
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[[Category: Potent antitumor effect]]
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[[Category: Structural protein]]
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Current revision

The structure of Aplyronine A-actin complex

PDB ID 1wua

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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