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5gi8
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine== | ==Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine== | ||
| - | <StructureSection load='5gi8' size='340' side='right' caption='[[5gi8]], [[Resolution|resolution]] 1.30Å' scene=''> | + | <StructureSection load='5gi8' size='340' side='right'caption='[[5gi8]], [[Resolution|resolution]] 1.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5gi8]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5gi8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GI8 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7DP:~{N}-[2-[3,4-bis(oxidanyl)phenyl]ethyl]ethanamide'>7DP</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=D1D:(4S,5S)-1,2-DITHIANE-4,5-DIOL'>D1D</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7DP:~{N}-[2-[3,4-bis(oxidanyl)phenyl]ethyl]ethanamide'>7DP</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=D1D:(4S,5S)-1,2-DITHIANE-4,5-DIOL'>D1D</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gi8 OCA], [https://pdbe.org/5gi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gi8 RCSB], [https://www.ebi.ac.uk/pdbsum/5gi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gi8 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DNAT_DROME DNAT_DROME] Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.<ref>PMID:8901578</ref> <ref>PMID:9703021</ref> <ref>PMID:7498465</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Drosophila melanogaster]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Cheng | + | [[Category: Cheng HC]] |
| - | [[Category: Cheng | + | [[Category: Cheng KC]] |
| - | [[Category: Lin | + | [[Category: Lin SJ]] |
| - | [[Category: Lyu | + | [[Category: Lyu PC]] |
| - | [[Category: Yang | + | [[Category: Yang YC]] |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine
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