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5gwp

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Current revision (11:44, 2 August 2023) (edit) (undo)
 
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<StructureSection load='5gwp' size='340' side='right'caption='[[5gwp]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
<StructureSection load='5gwp' size='340' side='right'caption='[[5gwp]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5gwp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GWP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5GWP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5gwp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa] and [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GWP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A8S:(2Z,4E)-5-[(1S)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>A8S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.577&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gwo|5gwo]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A8S:(2Z,4E)-5-[(1S)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>A8S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gwp OCA], [https://pdbe.org/5gwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gwp RCSB], [https://www.ebi.ac.uk/pdbsum/5gwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gwp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5gwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gwp OCA], [http://pdbe.org/5gwp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gwp RCSB], [http://www.ebi.ac.uk/pdbsum/5gwp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gwp ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYL3_ORYSJ PYL3_ORYSJ] Involved in abscisic acid (ABA) signaling during seed germination and abiotic stress response. Acts as positive regulator of ABA-mediated inhibition of seed germination, and tolerance to drought and cold stresses (PubMed:26362328). Together with PP2C50 and SAPK10, may form an ABA signaling module involved in stress response (PubMed:28827170). Inhibits the protein phosphatases PP2C06 and PP2C09 when activated by abscisic acid (ABA) (PubMed:24743650).<ref>PMID:24743650</ref> <ref>PMID:26362328</ref> <ref>PMID:28827170</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Phosphoprotein phosphatase]]
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[[Category: Oryza sativa]]
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[[Category: Han, S]]
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[[Category: Oryza sativa Japonica Group]]
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[[Category: Lee, S]]
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[[Category: Han S]]
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[[Category: Aba receptor]]
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[[Category: Lee S]]
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[[Category: Abscisic acid]]
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[[Category: Hydrolase-receptor complex]]
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[[Category: Pp2c]]
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Current revision

Crystal structure of RCAR3:PP2C wild-type with (+)-ABA

PDB ID 5gwp

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