8g9v

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Current revision (05:28, 9 August 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8g9v is ON HOLD until Paper Publication
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==Crystal structures of 17-beta-hydroxysteroid dehydrogenase 13==
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<StructureSection load='8g9v' size='340' side='right'caption='[[8g9v]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8g9v]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G9V FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.645&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE1:O-DODECANYL+OCTAETHYLENE+GLYCOL'>CE1</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YYC:4-{[2,5-dimethyl-3-(4-methylbenzene-1-sulfonyl)benzene-1-sulfonyl]amino}benzoic+acid'>YYC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g9v OCA], [https://pdbe.org/8g9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g9v RCSB], [https://www.ebi.ac.uk/pdbsum/8g9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g9v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DHB13_HUMAN DHB13_HUMAN] Plays a pivotal role in hepatic lipid metabolism (PubMed:29562163). In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4 (PubMed:29562163, PubMed:30415504, PubMed:32973038).<ref>PMID:29562163</ref> <ref>PMID:30415504</ref> <ref>PMID:32973038</ref> Has retinol/retinal dehydrogenase activity in vitro.<ref>PMID:30415504</ref> <ref>PMID:32973038</ref> Does not have retinol/retinal dehydrogenase activity in vitro.<ref>PMID:30415504</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Liu S]]

Current revision

Crystal structures of 17-beta-hydroxysteroid dehydrogenase 13

PDB ID 8g9v

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