8jpe
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes== | |
| - | + | <StructureSection load='8jpe' size='340' side='right'caption='[[8jpe]], [[Resolution|resolution]] 2.91Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8jpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JPE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.91Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jpe OCA], [https://pdbe.org/8jpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jpe RCSB], [https://www.ebi.ac.uk/pdbsum/8jpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jpe ProSAT]</span></td></tr> |
| - | [[Category: Duan | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: Liu | + | [https://www.uniprot.org/uniprot/GNAQ_HUMAN GNAQ_HUMAN] Sturge-Weber syndrome;Phakomatosis cesioflammea;Uveal melanoma;Familial multiple nevi flammei. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. |
| - | [[Category: Yuan | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/GNAQ_HUMAN GNAQ_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Duan J]] | ||
| + | [[Category: Ji Y]] | ||
| + | [[Category: Liu H]] | ||
| + | [[Category: Xu HE]] | ||
| + | [[Category: Yuan Q]] | ||
| + | [[Category: Zhao F]] | ||
Current revision
Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes
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Categories: Homo sapiens | Large Structures | Duan J | Ji Y | Liu H | Xu HE | Yuan Q | Zhao F
