8oo6

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'''Unreleased structure'''
 
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The entry 8oo6 is ON HOLD until sometime in the future
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==Pol I bound to extended and displaced DNA section - closed conformation==
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<StructureSection load='8oo6' size='340' side='right'caption='[[8oo6]], [[Resolution|resolution]] 4.30&Aring;' scene=''>
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Authors: Botto, M., Borsellini, A., Lamers, M.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8oo6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_'BL21-Gold(DE3)pLysS_AG' Escherichia coli 'BL21-Gold(DE3)pLysS AG'] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OO6 FirstGlance]. <br>
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Description: Structure of E. coli DNA Polymerase I ''closed conformation''
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Borsellini, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8oo6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8oo6 OCA], [https://pdbe.org/8oo6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8oo6 RCSB], [https://www.ebi.ac.uk/pdbsum/8oo6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8oo6 ProSAT]</span></td></tr>
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[[Category: Botto, M]]
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</table>
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[[Category: Lamers, M.H]]
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== Function ==
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[https://www.uniprot.org/uniprot/DPO1_ECOLI DPO1_ECOLI] In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Borsellini A]]
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[[Category: Botto M]]
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[[Category: Lamers MH]]

Revision as of 05:31, 9 August 2023

Pol I bound to extended and displaced DNA section - closed conformation

PDB ID 8oo6

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