1c3l

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Current revision (05:47, 9 August 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1c3l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C3L FirstGlance]. <br>
<table><tr><td colspan='2'>[[1c3l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C3L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sbc|1sbc]], [[1bfu|1bfu]], [[1bfk|1bfk]], [[1sca|1sca]], [[1av7|1av7]], [[1avt|1avt]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c3l OCA], [https://pdbe.org/1c3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c3l RCSB], [https://www.ebi.ac.uk/pdbsum/1c3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c3l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c3l OCA], [https://pdbe.org/1c3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c3l RCSB], [https://www.ebi.ac.uk/pdbsum/1c3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c3l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SUBT_BACLI SUBT_BACLI]] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
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[https://www.uniprot.org/uniprot/SUBC_BACLI SUBC_BACLI] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides (Ref.4, PubMed:11109488). Shows high specificity for aromatic and hydrophobic amino acids in the P1 substrate position (PubMed:11109488). May play an important role in the degradation of feather keratin (PubMed:11109488).<ref>PMID:11109488</ref> <ref>PMID:4967581</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Bacillus licheniformis]]
[[Category: Bacillus licheniformis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Subtilisin]]
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[[Category: Colloc'h N]]
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[[Category: Longhi, S]]
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[[Category: Longhi S]]
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[[Category: Pernot, L]]
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[[Category: Pernot L]]
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[[Category: Prange, T]]
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[[Category: Prange T]]
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[[Category: Schiltz, M]]
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[[Category: Schiltz M]]
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[[Category: H, N Colloc]]
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[[Category: Hydrolase]]
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[[Category: Serine-proteinase]]
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[[Category: Xenon]]
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Current revision

SUBTILISIN-CARLSBERG COMPLEXED WITH XENON (8 BAR)

PDB ID 1c3l

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