1ce2

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ce2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bubalus_bubalis Bubalus bubalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CE2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ce2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bubalus_bubalis Bubalus bubalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CE2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ce2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ce2 OCA], [https://pdbe.org/1ce2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ce2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ce2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ce2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ce2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ce2 OCA], [https://pdbe.org/1ce2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ce2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ce2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ce2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TRFL_BUBBU TRFL_BUBBU]] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity).
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[https://www.uniprot.org/uniprot/TRFL_BUBBU TRFL_BUBBU] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Bubalus bubalis]]
[[Category: Bubalus bubalis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Karthikeyan, S]]
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[[Category: Karthikeyan S]]
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[[Category: Paramasivam, M]]
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[[Category: Paramasivam M]]
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[[Category: Singh, T P]]
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[[Category: Singh TP]]
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[[Category: Srinivasan, A]]
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[[Category: Srinivasan A]]
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[[Category: Yadav, S]]
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[[Category: Yadav S]]
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[[Category: Antibacterial]]
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[[Category: Iron binding protein]]
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[[Category: Lactoferrin]]
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[[Category: Metal transport]]
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[[Category: Room temperature]]
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Revision as of 05:50, 9 August 2023

STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN AT 2.5A RESOLUTION

PDB ID 1ce2

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