1fao

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<StructureSection load='1fao' size='340' side='right'caption='[[1fao]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1fao' size='340' side='right'caption='[[1fao]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1fao]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FAO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1fao]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FAO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4IP:INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE'>4IP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fb8|1fb8]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4IP:INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE'>4IP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fao OCA], [https://pdbe.org/1fao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fao RCSB], [https://www.ebi.ac.uk/pdbsum/1fao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fao ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fao OCA], [https://pdbe.org/1fao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fao RCSB], [https://www.ebi.ac.uk/pdbsum/1fao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fao ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DAPP1_HUMAN DAPP1_HUMAN]] May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.<ref>PMID:10770799</ref>
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[https://www.uniprot.org/uniprot/DAPP1_HUMAN DAPP1_HUMAN] May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.<ref>PMID:10770799</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ferguson, K M]]
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[[Category: Ferguson KM]]
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[[Category: Fournier, E]]
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[[Category: Fournier E]]
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[[Category: Isakoff, S J]]
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[[Category: Isakoff SJ]]
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[[Category: Kavran, J M]]
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[[Category: Kavran JM]]
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[[Category: Lemmon, M A]]
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[[Category: Lemmon MA]]
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[[Category: Sankaran, V G]]
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[[Category: Sankaran VG]]
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[[Category: Skolnik, E Y]]
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[[Category: Skolnik EY]]
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[[Category: 3-phosphoinositide]]
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[[Category: Adaptor protein]]
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[[Category: Inositol tetrakisphosphate signal transduction protein]]
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[[Category: Pleckstrin]]
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[[Category: Signaling protein]]
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Revision as of 06:02, 9 August 2023

STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE

PDB ID 1fao

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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