1g41

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Current revision (06:07, 9 August 2023) (edit) (undo)
 
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<StructureSection load='1g41' size='340' side='right'caption='[[1g41]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1g41' size='340' side='right'caption='[[1g41]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1g41]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G41 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G41 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1g41]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G41 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G41 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1do0|1do0]], [[1do2|1do2]], [[1doo|1doo]], [[1g3i|1g3i]], [[1g3k|1g3k]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g41 OCA], [https://pdbe.org/1g41 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g41 RCSB], [https://www.ebi.ac.uk/pdbsum/1g41 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g41 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g41 OCA], [https://pdbe.org/1g41 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g41 RCSB], [https://www.ebi.ac.uk/pdbsum/1g41 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g41 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/HSLU_HAEIN HSLU_HAEIN]] ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
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[https://www.uniprot.org/uniprot/HSLU_HAEIN HSLU_HAEIN] ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Haemophilus influenzae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: McKay, D B]]
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[[Category: McKay DB]]
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[[Category: Trame, C B]]
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[[Category: Trame CB]]
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[[Category: Aaa-atpase]]
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[[Category: Atp-dependent proteolysis]]
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[[Category: Chaperone]]
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[[Category: Clpy]]
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Current revision

CRYSTAL STRUCTURE OF HSLU HAEMOPHILUS INFLUENZAE

PDB ID 1g41

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