1hx9
From Proteopedia
(Difference between revisions)
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<StructureSection load='1hx9' size='340' side='right'caption='[[1hx9]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='1hx9' size='340' side='right'caption='[[1hx9]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1hx9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1hx9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HX9 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hx9 OCA], [https://pdbe.org/1hx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hx9 RCSB], [https://www.ebi.ac.uk/pdbsum/1hx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hx9 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hx9 OCA], [https://pdbe.org/1hx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hx9 RCSB], [https://www.ebi.ac.uk/pdbsum/1hx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hx9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: American tobacco]] | ||
| - | [[Category: Aristolochene synthase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Nicotiana tabacum]] |
| - | [[Category: | + | [[Category: Chappell J]] |
| - | [[Category: | + | [[Category: Noel JP]] |
| - | [[Category: | + | [[Category: Rising KA]] |
| - | [[Category: | + | [[Category: Starks CS]] |
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Current revision
CRYSTAL STRUCTURE OF TEAS W273S FORM 1
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