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2tdt

From Proteopedia

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Current revision (06:46, 9 August 2023) (edit) (undo)
 
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<StructureSection load='2tdt' size='340' side='right'caption='[[2tdt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2tdt' size='340' side='right'caption='[[2tdt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2tdt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"mycobacterium_tuberculosis_typus_bovinus"_lehmann_and_neumann_1907 "mycobacterium tuberculosis typus bovinus" lehmann and neumann 1907]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TDT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2TDT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2tdt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_variant_bovis Mycobacterium tuberculosis variant bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TDT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2TDT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=NPI:(2S)-2-AMINOHEPTANEDIOIC+ACID'>NPI</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DAPD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1765 "Mycobacterium tuberculosis typus bovinus" Lehmann and Neumann 1907])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=NPI:(2S)-2-AMINOHEPTANEDIOIC+ACID'>NPI</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2,3,4,5-tetrahydropyridine-2,6-dicarboxylate_N-succinyltransferase 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.117 2.3.1.117] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2tdt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tdt OCA], [https://pdbe.org/2tdt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2tdt RCSB], [https://www.ebi.ac.uk/pdbsum/2tdt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2tdt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2tdt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tdt OCA], [https://pdbe.org/2tdt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2tdt RCSB], [https://www.ebi.ac.uk/pdbsum/2tdt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2tdt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DAPD_MYCBO DAPD_MYCBO]] Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA (By similarity).
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[https://www.uniprot.org/uniprot/DAPD_UNKP DAPD_UNKP]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium tuberculosis typus bovinus lehmann and neumann 1907]]
 
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[[Category: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Beaman, T W]]
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[[Category: Mycobacterium tuberculosis variant bovis]]
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[[Category: Blanchard, J S]]
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[[Category: Beaman TW]]
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[[Category: Roderick, S L]]
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[[Category: Blanchard JS]]
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[[Category: Acyltransferase]]
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[[Category: Roderick SL]]
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[[Category: Lysine biosynthesis]]
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Current revision

COMPLEX OF TETRAHYDRODIPICOLINATE N-SUCCINYLTRANSFERASE WITH 2-AMINOPIMELATE AND COENZYME A

PDB ID 2tdt

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