5h7t

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Current revision (07:26, 9 August 2023) (edit) (undo)
 
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<StructureSection load='5h7t' size='340' side='right'caption='[[5h7t]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
<StructureSection load='5h7t' size='340' side='right'caption='[[5h7t]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5h7t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H7T OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5H7T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5h7t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptomeria_japonica Cryptomeria japonica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5H7T FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.19&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5h7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h7t OCA], [http://pdbe.org/5h7t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h7t RCSB], [http://www.ebi.ac.uk/pdbsum/5h7t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h7t ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5h7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h7t OCA], [https://pdbe.org/5h7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5h7t RCSB], [https://www.ebi.ac.uk/pdbsum/5h7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5h7t ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CHI4_CRYJA CHI4_CRYJA] Has endochitinase activity (PubMed:15725197). Hydrolyzes chitin oligosaccharides, GlcNAc(n), with different degrees of polymerization (n=2-6), a soluble substrate glycol chitin, and an insoluble substrate beta-chitin nanofiber in vitro. GlcNAc(6) is hydrolyzed at the second glycosidic linkage from the reducing end in addition to the middle linkage. GlcNAc(4) is further hydrolyzed to GlcNAc(2). Has antifungal activity against hyphal growth of H.rufa (PubMed:29756783).<ref>PMID:15725197</ref> <ref>PMID:29756783</ref>
==See Also==
==See Also==
*[[Chitinase 3D structures|Chitinase 3D structures]]
*[[Chitinase 3D structures|Chitinase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chitinase]]
 
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[[Category: Large Structures]]
 
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[[Category: Fukamizo, T]]
 
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[[Category: Numata, T]]
 
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[[Category: Ohnuma, T]]
 
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[[Category: Takashima, T]]
 
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[[Category: Umemoto, N]]
 
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[[Category: Allergen]]
 
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[[Category: Cjp-4]]
 
[[Category: Cryptomeria japonica]]
[[Category: Cryptomeria japonica]]
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[[Category: Gh19 chitinase]]
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[[Category: Large Structures]]
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[[Category: Hydrolase]]
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[[Category: Fukamizo T]]
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[[Category: Numata T]]
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[[Category: Ohnuma T]]
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[[Category: Takashima T]]
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[[Category: Umemoto N]]

Current revision

A GH19 chitinase domain from the Cryptomeria japnonica pollen (CJP-4) allergen

PDB ID 5h7t

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