From Proteopedia
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| - | ==Bovine Xanthine Oxidoreductase Crystallized with oxypurinol==
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| - | <StructureSection load='8hxm' size='340' side='right'caption='[[8hxm]], [[Resolution|resolution]] 1.99Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[8hxm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HXM FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=141:OXYPURINOL'>141</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MOS:DIOXOTHIOMOLYBDENUM(VI)+ION'>MOS</scene>, <scene name='pdbligand=MTE:PHOSPHONIC+ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER'>MTE</scene></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hxm OCA], [https://pdbe.org/8hxm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hxm RCSB], [https://www.ebi.ac.uk/pdbsum/8hxm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hxm ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [https://www.uniprot.org/uniprot/XDH_BOVIN XDH_BOVIN] Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species.
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Bos taurus]]
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| - | [[Category: Large Structures]]
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| - | [[Category: Okamoto K]]
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| - | [[Category: Sekine M]]
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Current revision
REMOVED: The PDB entry 8hxm was removed.
