8ixe

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'''Unreleased structure'''
 
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The entry 8ixe is ON HOLD until Paper Publication
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==GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region==
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<StructureSection load='8ixe' size='340' side='right'caption='[[8ixe]], [[Resolution|resolution]] 4.40&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ixe]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IXE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IXE FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ixe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ixe OCA], [https://pdbe.org/8ixe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ixe RCSB], [https://www.ebi.ac.uk/pdbsum/8ixe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ixe ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TBA1C_MOUSE TBA1C_MOUSE] Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Bao L]]
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[[Category: Cong Y]]
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[[Category: Diao L]]
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[[Category: Zhao QY]]
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[[Category: Zheng W]]

Revision as of 08:26, 16 August 2023

GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region

PDB ID 8ixe

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OCA

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