1m1n

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[[Image:1m1n.gif|left|200px]]
[[Image:1m1n.gif|left|200px]]
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{{Structure
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|PDB= 1m1n |SIZE=350|CAPTION= <scene name='initialview01'>1m1n</scene>, resolution 1.16&Aring;
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The line below this paragraph, containing "STRUCTURE_1m1n", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CFN:FE(7)-MO-S(9)-N+CLUSTER'>CFN</scene>, <scene name='pdbligand=CLF:FE(8)-S(7)+CLUSTER'>CLF</scene>, <scene name='pdbligand=HCA:3-HYDROXY-3-CARBOXY-ADIPIC+ACID'>HCA</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrogenase Nitrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.6.1 1.18.6.1] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1m1n| PDB=1m1n | SCENE= }}
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|RELATEDENTRY=[[3min|3min]], [[2min|2min]], [[1n2c|1n2c]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1n OCA], [http://www.ebi.ac.uk/pdbsum/1m1n PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1m1n RCSB]</span>
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'''Nitrogenase MoFe protein from Azotobacter vinelandii'''
'''Nitrogenase MoFe protein from Azotobacter vinelandii'''
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[[Category: Tezcan, F A.]]
[[Category: Tezcan, F A.]]
[[Category: Yoshida, M.]]
[[Category: Yoshida, M.]]
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[[Category: atomic resolution]]
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[[Category: Atomic resolution]]
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[[Category: central nitrogen ligand]]
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[[Category: Central nitrogen ligand]]
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[[Category: femo cofactor]]
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[[Category: Femo cofactor]]
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[[Category: nitrogen fixation]]
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[[Category: Nitrogen fixation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:31:31 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:10:06 2008''
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Revision as of 21:31, 2 May 2008

Image:1m1n.gif

Template:STRUCTURE 1m1n

Nitrogenase MoFe protein from Azotobacter vinelandii


Overview

A high-resolution crystallographic analysis of the nitrogenase MoFe-protein reveals a previously unrecognized ligand coordinated to six iron atoms in the center of the catalytically essential FeMo-cofactor. The electron density for this ligand is masked in structures with resolutions lower than 1.55 angstroms, owing to Fourier series termination ripples from the surrounding iron and sulfur atoms in the cofactor. The central atom completes an approximate tetrahedral coordination for the six iron atoms, instead of the trigonal coordination proposed on the basis of lower resolution structures. The crystallographic refinement at 1.16 angstrom resolution is consistent with this newly detected component being a light element, most plausibly nitrogen. The presence of a nitrogen atom in the cofactor would have important implications for the mechanism of dinitrogen reduction by nitrogenase.

About this Structure

1M1N is a Protein complex structure of sequences from Azotobacter vinelandii. Full crystallographic information is available from OCA.

Reference

Nitrogenase MoFe-protein at 1.16 A resolution: a central ligand in the FeMo-cofactor., Einsle O, Tezcan FA, Andrade SL, Schmid B, Yoshida M, Howard JB, Rees DC, Science. 2002 Sep 6;297(5587):1696-700. PMID:12215645 Page seeded by OCA on Sat May 3 00:31:31 2008

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