1kv5

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Current revision (09:05, 16 August 2023) (edit) (undo)
 
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<StructureSection load='1kv5' size='340' side='right'caption='[[1kv5]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='1kv5' size='340' side='right'caption='[[1kv5]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1kv5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KV5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1kv5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KV5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kv5 OCA], [https://pdbe.org/1kv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kv5 RCSB], [https://www.ebi.ac.uk/pdbsum/1kv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kv5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kv5 OCA], [https://pdbe.org/1kv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kv5 RCSB], [https://www.ebi.ac.uk/pdbsum/1kv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kv5 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPIS_TRYBB TPIS_TRYBB]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Triose-phosphate isomerase]]
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[[Category: Trypanosoma brucei brucei]]
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[[Category: Trybb]]
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[[Category: Kursula I]]
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[[Category: Kursula, I]]
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[[Category: Lambeir A-M]]
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[[Category: Lambeir, A M]]
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[[Category: Partanen S]]
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[[Category: Partanen, S]]
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[[Category: Wierenga RK]]
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[[Category: Wierenga, R K]]
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[[Category: Isomerase]]
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[[Category: Mutant]]
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[[Category: Salt bridge]]
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[[Category: Tim barrel]]
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Current revision

Structure of Trypanosoma brucei brucei TIM with the salt-bridge-forming residue Arg191 mutated to Ser

PDB ID 1kv5

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