This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.




1m2e

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1m2e.jpg|left|200px]]
[[Image:1m2e.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1m2e |SIZE=350|CAPTION= <scene name='initialview01'>1m2e</scene>
+
The line below this paragraph, containing "STRUCTURE_1m2e", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= kaiA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32046 Synechococcus elongatus])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1m2e| PDB=1m2e | SCENE= }}
-
|RELATEDENTRY=[[1m2f|1M2F]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m2e OCA], [http://www.ebi.ac.uk/pdbsum/1m2e PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1m2e RCSB]</span>
+
-
}}
+
'''Solution structure of the N-terminal domain of Synechococcus elongatus KaiA (KaiA135N); Average minimized structure.'''
'''Solution structure of the N-terminal domain of Synechococcus elongatus KaiA (KaiA135N); Average minimized structure.'''
Line 29: Line 26:
[[Category: Vakonakis, I.]]
[[Category: Vakonakis, I.]]
[[Category: Williams, S B.]]
[[Category: Williams, S B.]]
-
[[Category: alpha-beta-alpha sandwich]]
+
[[Category: Alpha-beta-alpha sandwich]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:33:03 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:10:25 2008''
+

Revision as of 21:33, 2 May 2008

Image:1m2e.jpg

Template:STRUCTURE 1m2e

Solution structure of the N-terminal domain of Synechococcus elongatus KaiA (KaiA135N); Average minimized structure.


Overview

In the cyanobacterium Synechococcus elongatus (PCC 7942) the proteins KaiA, KaiB, and KaiC are required for circadian clock function. We deduced a circadian clock function for KaiA from a combination of biochemical and structural data. Both KaiA and its isolated carboxyl-terminal domain (KaiA180C) stimulated KaiC autophosphorylation and facilitated attenuation of KaiC autophosphorylation by KaiB. An amino-terminal domain (KaiA135N) had no function in the autophosphorylation assay. NMR structure determination showed that KaiA135N is a pseudo-receiver domain. We propose that this pseudo-receiver is a timing input-device that regulates KaiA stimulation of KaiC autophosphorylation, which in turn is essential for circadian timekeeping.

About this Structure

1M2E is a Single protein structure of sequence from Synechococcus elongatus. Full crystallographic information is available from OCA.

Reference

Structure and function from the circadian clock protein KaiA of Synechococcus elongatus: a potential clock input mechanism., Williams SB, Vakonakis I, Golden SS, LiWang AC, Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15357-62. Epub 2002 Nov 15. PMID:12438647 Page seeded by OCA on Sat May 3 00:33:03 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1m2e"
Personal tools