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1otx

From Proteopedia

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Current revision (09:32, 16 August 2023) (edit) (undo)
 
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<StructureSection load='1otx' size='340' side='right'caption='[[1otx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='1otx' size='340' side='right'caption='[[1otx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1otx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1otx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ecp|1ecp]], [[1a90|1a90]], [[1oty|1oty]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otx OCA], [https://pdbe.org/1otx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otx RCSB], [https://www.ebi.ac.uk/pdbsum/1otx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otx OCA], [https://pdbe.org/1otx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otx RCSB], [https://www.ebi.ac.uk/pdbsum/1otx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DEOD_ECOLI DEOD_ECOLI]] Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules.[HAMAP-Rule:MF_01627]
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[https://www.uniprot.org/uniprot/DEOD_ECOLI DEOD_ECOLI] Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules.[HAMAP-Rule:MF_01627]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Purine-nucleoside phosphorylase]]
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[[Category: Allan PW]]
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[[Category: Allan, P W]]
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[[Category: Anand R]]
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[[Category: Anand, R]]
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[[Category: Bennett EM]]
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[[Category: Bennett, E M]]
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[[Category: Ealick SE]]
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[[Category: Ealick, S E]]
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[[Category: Hassan AE]]
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[[Category: Hassan, A E]]
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[[Category: McPherson DT]]
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[[Category: McPherson, D T]]
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[[Category: Parker WB]]
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[[Category: Parker, W B]]
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[[Category: Secrist JA]]
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[[Category: Secrist, J A]]
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[[Category: Sorscher EJ]]
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[[Category: Sorscher, E J]]
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[[Category: Empty]]
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[[Category: Pnp]]
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[[Category: Transferase]]
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Current revision

Purine Nucleoside Phosphorylase M64V mutant

PDB ID 1otx

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OCA

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