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1p7n

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Current revision (09:39, 16 August 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1p7n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P7N FirstGlance]. <br>
<table><tr><td colspan='2'>[[1p7n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P7N FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1em9|1em9]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p7n OCA], [https://pdbe.org/1p7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p7n RCSB], [https://www.ebi.ac.uk/pdbsum/1p7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p7n ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p7n OCA], [https://pdbe.org/1p7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p7n RCSB], [https://www.ebi.ac.uk/pdbsum/1p7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p7n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP]] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
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[https://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Rous sarcoma virus]]
[[Category: Rous sarcoma virus]]
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[[Category: Francisco, A B]]
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[[Category: Francisco AB]]
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[[Category: Johnson, M C]]
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[[Category: Johnson MC]]
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[[Category: Nandhagopal, N]]
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[[Category: Nandhagopal N]]
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[[Category: Rossmann, M G]]
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[[Category: Rossmann MG]]
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[[Category: Schatz, G W]]
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[[Category: Schatz GW]]
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[[Category: Simpson, A A]]
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[[Category: Simpson AA]]
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[[Category: Vogt, V M]]
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[[Category: Vogt VM]]
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[[Category: Capsid protein]]
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[[Category: Gag polyprotein]]
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[[Category: Immature gag]]
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[[Category: Retrovirus]]
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[[Category: Viral protein]]
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Current revision

Dimeric Rous Sarcoma virus Capsid protein structure with an upstream 25-amino acid residue extension of C-terminal of Gag p10 protein

PDB ID 1p7n

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