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2xda

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Current revision (10:38, 16 August 2023) (edit) (undo)
 
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<StructureSection load='2xda' size='340' side='right'caption='[[2xda]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='2xda' size='340' side='right'caption='[[2xda]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xda]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XDA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xda]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XDA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JPS:(4R,6R,7S)-2-(2-CYCLOPROPYLETHYL)-4,6,7-TRIHYDROXY-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC+ACID'>JPS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2c57|2c57]], [[2wks|2wks]], [[2c4v|2c4v]], [[1j2y|1j2y]], [[2xb9|2xb9]], [[2c4w|2c4w]], [[2xd9|2xd9]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JPS:(4R,6R,7S)-2-(2-CYCLOPROPYLETHYL)-4,6,7-TRIHYDROXY-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC+ACID'>JPS</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xda OCA], [https://pdbe.org/2xda PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xda RCSB], [https://www.ebi.ac.uk/pdbsum/2xda PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xda ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xda OCA], [https://pdbe.org/2xda PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xda RCSB], [https://www.ebi.ac.uk/pdbsum/2xda PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xda ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AROQ_HELPY AROQ_HELPY]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
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[https://www.uniprot.org/uniprot/AROQ_HELPY AROQ_HELPY] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-dehydroquinate dehydratase]]
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[[Category: Helicobacter pylori]]
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[[Category: Atcc 43504]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Castedo, L]]
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[[Category: Castedo L]]
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[[Category: Fox, G C]]
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[[Category: Fox GC]]
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[[Category: Gonzalez-Bello, C]]
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[[Category: Gonzalez-Bello C]]
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[[Category: Hawkins, A R]]
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[[Category: Hawkins AR]]
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[[Category: Lamb, H]]
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[[Category: Lamb H]]
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[[Category: Llamas-Saiz, A L]]
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[[Category: Llamas-Saiz AL]]
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[[Category: Otero, J M]]
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[[Category: Otero JM]]
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[[Category: Paz, S]]
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[[Category: Paz S]]
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[[Category: Raaij, M J.van]]
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[[Category: Tizon L]]
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[[Category: Tizon, L]]
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[[Category: Van Raaij MJ]]
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[[Category: Aromatic amino acid biosynthesis]]
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[[Category: Lyase]]
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Current revision

STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-2-(2-Cyclopropyl)ethyl-4,6,7- trihydroxy-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid

PDB ID 2xda

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