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3d4c

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Current revision (10:40, 16 August 2023) (edit) (undo)
 
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<StructureSection load='3d4c' size='340' side='right'caption='[[3d4c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='3d4c' size='340' side='right'caption='[[3d4c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3d4c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D4C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3d4c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D4C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3d4g|3d4g]], [[3ef7|3ef7]], [[3nk3|3nk3]], [[3nk4|3nk4]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Zp3, Zp-3, Zpc ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d4c OCA], [https://pdbe.org/3d4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d4c RCSB], [https://www.ebi.ac.uk/pdbsum/3d4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d4c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d4c OCA], [https://pdbe.org/3d4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d4c RCSB], [https://www.ebi.ac.uk/pdbsum/3d4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d4c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI]] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.
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[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/ZP3_MOUSE ZP3_MOUSE] Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Jovine, L]]
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[[Category: Jovine L]]
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[[Category: Monne, M]]
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[[Category: Monne M]]
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[[Category: Biodiversity]]
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[[Category: Cell adhesion]]
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[[Category: Egg coat]]
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[[Category: Egg-sperm interaction]]
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[[Category: Extracellular matrix]]
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[[Category: Fertilization]]
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[[Category: Glycoprotein]]
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[[Category: Immunoglobulin-like fold]]
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[[Category: Infertility]]
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[[Category: Oocyte]]
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[[Category: Receptor]]
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[[Category: Secreted]]
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[[Category: Speciation]]
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[[Category: Species-specific gamete recognition]]
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[[Category: Transmembrane]]
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[[Category: Vitelline envelope]]
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[[Category: Zona pellucida]]
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[[Category: Zp domain]]
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Current revision

ZP-N domain of mammalian sperm receptor ZP3 (crystal form I)

PDB ID 3d4c

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