5hs5

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<StructureSection load='5hs5' size='340' side='right'caption='[[5hs5]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='5hs5' size='340' side='right'caption='[[5hs5]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hs5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa3 Staa3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HS5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HS5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hs5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_USA300 Staphylococcus aureus subsp. aureus USA300]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HS5 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sarX, SAUSA300_0654 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=367830 STAA3])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hs5 OCA], [http://pdbe.org/5hs5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hs5 RCSB], [http://www.ebi.ac.uk/pdbsum/5hs5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hs5 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hs5 OCA], [https://pdbe.org/5hs5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hs5 RCSB], [https://www.ebi.ac.uk/pdbsum/5hs5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hs5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SARX_STAA3 SARX_STAA3]] Involved in the regulation of virulence genes. Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb. Binds directly to the agr promoter region (By similarity).
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[https://www.uniprot.org/uniprot/SARX_STAA8 SARX_STAA8] Involved in the regulation of virulence genes. Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb. Binds directly to the agr promoter region.<ref>PMID:16740935</ref>
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staa3]]
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[[Category: Staphylococcus aureus subsp. aureus USA300]]
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[[Category: Li, X]]
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[[Category: Li X]]
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[[Category: Song, Y]]
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[[Category: Song Y]]
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[[Category: Teng, M K]]
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[[Category: Teng MK]]
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[[Category: Zhang, F]]
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[[Category: Zhang F]]
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[[Category: Sarx]]
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[[Category: Staphylococcus aureus]]
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[[Category: Transcriptional regulator]]
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[[Category: Virulence regulator]]
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Current revision

Crystal structure of Staphylococcus aureus SarX

PDB ID 5hs5

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