5hwl

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Current revision (10:57, 16 August 2023) (edit) (undo)
 
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<StructureSection load='5hwl' size='340' side='right'caption='[[5hwl]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='5hwl' size='340' side='right'caption='[[5hwl]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hwl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HWL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HWL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hwl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HWL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=NNE:N,N-(butane-1,4-diyl)bis{2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetamide}'>NNE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xw5|1xw5]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=NNE:N,N-(butane-1,4-diyl)bis{2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetamide}'>NNE</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hwl OCA], [https://pdbe.org/5hwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hwl RCSB], [https://www.ebi.ac.uk/pdbsum/5hwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hwl ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hwl OCA], [http://pdbe.org/5hwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hwl RCSB], [http://www.ebi.ac.uk/pdbsum/5hwl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hwl ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GSTM2_HUMAN GSTM2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:16549767</ref>
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[https://www.uniprot.org/uniprot/GSTM2_HUMAN GSTM2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:16549767</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glutathione transferase]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Liao, F]]
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[[Category: Liao F]]
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[[Category: Luo, M]]
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[[Category: Luo M]]
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[[Category: Wang, D Q]]
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[[Category: Wang DQ]]
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[[Category: Wei, J]]
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[[Category: Wei J]]
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[[Category: Wu, S]]
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[[Category: Wu S]]
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[[Category: Yang, X L]]
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[[Category: Yang XL]]
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[[Category: Zhang, H P]]
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[[Category: Zhang HP]]
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[[Category: Zhang, X]]
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[[Category: Zhang X]]
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[[Category: Complex]]
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[[Category: Inhibitor]]
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[[Category: Target]]
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[[Category: Transferase]]
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Current revision

Human glutathione s-transferase Mu2 complexed with BDEA, monoclinic crystal form

PDB ID 5hwl

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