1rm1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:05, 23 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='1rm1' size='340' side='right'caption='[[1rm1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1rm1' size='340' side='right'caption='[[1rm1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1rm1]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RM1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1RM1 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1rm1]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RM1 FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPT15, BTF1, YER148W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824]), TOA2, YKL058W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824]), TOA1, YOR194C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1rm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rm1 OCA], [http://pdbe.org/1rm1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rm1 RCSB], [http://www.ebi.ac.uk/pdbsum/1rm1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1rm1 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rm1 OCA], [https://pdbe.org/1rm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rm1 RCSB], [https://www.ebi.ac.uk/pdbsum/1rm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rm1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/T2AG_YEAST T2AG_YEAST]] TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.<ref>PMID:1918049</ref> [[http://www.uniprot.org/uniprot/TBP_YEAST TBP_YEAST]] General transcription factor that functions at the core of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.<ref>PMID:9618449</ref> <ref>PMID:12138208</ref> <ref>PMID:12516863</ref> [[http://www.uniprot.org/uniprot/TOA1_YEAST TOA1_YEAST]] TFIIA is a component of the transcription machinery of RNA polymerase II and implicated in the regulation of basal transcription. Interacts with TBP (the TATA-binding protein).
+
[https://www.uniprot.org/uniprot/TBP_YEAST TBP_YEAST] General transcription factor that functions at the core of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.<ref>PMID:9618449</ref> <ref>PMID:12138208</ref> <ref>PMID:12516863</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 27: Line 27:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 18824]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Geiger, J H]]
+
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Gewirth, D T]]
+
[[Category: Geiger JH]]
-
[[Category: Jin, X]]
+
[[Category: Gewirth DT]]
-
[[Category: Ata-box dna]]
+
[[Category: Jin X]]
-
[[Category: Tbp protein]]
+
-
[[Category: Transcription-dna complex]]
+
-
[[Category: Yeast tfiia]]
+

Current revision

Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex

PDB ID 1rm1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rm1"
Personal tools