This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1rm6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:06, 23 August 2023) (edit) (undo)
 
Line 4: Line 4:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1rm6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thauera_aromatica Thauera aromatica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RM6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1rm6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thauera_aromatica Thauera aromatica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RM6 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/4-hydroxybenzoyl-CoA_reductase 4-hydroxybenzoyl-CoA reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.7.9 1.3.7.9] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rm6 OCA], [https://pdbe.org/1rm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rm6 RCSB], [https://www.ebi.ac.uk/pdbsum/1rm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rm6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rm6 OCA], [https://pdbe.org/1rm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rm6 RCSB], [https://www.ebi.ac.uk/pdbsum/1rm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rm6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/HCRA_THAAR HCRA_THAAR]] Component of a complex that catalyzes the reductive dehydroxylation of 4-hydroxybenzoyl-CoA to benzoyl-CoA. Reaction is not reversible. Is a key enzyme in the anaerobic degradation of phenolic compounds.<ref>PMID:9490068</ref> [[https://www.uniprot.org/uniprot/HCRC_THAAR HCRC_THAAR]] Component of a complex that catalyzes the reductive dehydroxylation of 4-hydroxybenzoyl-CoA to benzoyl-CoA. Reaction is not reversible. Is a key enzyme in the anaerobic degradation of phenolic compounds.<ref>PMID:9490068</ref> [[https://www.uniprot.org/uniprot/HCRB_THAAR HCRB_THAAR]] Component of a complex that catalyzes the reductive dehydroxylation of 4-hydroxybenzoyl-CoA to benzoyl-CoA. Reaction is not reversible. Is a key enzyme in the anaerobic degradation of phenolic compounds.<ref>PMID:9490068</ref>
+
[https://www.uniprot.org/uniprot/HCRA_THAAR HCRA_THAAR] Component of a complex that catalyzes the reductive dehydroxylation of 4-hydroxybenzoyl-CoA to benzoyl-CoA. Reaction is not reversible. Is a key enzyme in the anaerobic degradation of phenolic compounds.<ref>PMID:9490068</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 33: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: 4-hydroxybenzoyl-CoA reductase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Thauera aromatica]]
[[Category: Thauera aromatica]]
-
[[Category: Boll, M]]
+
[[Category: Boll M]]
-
[[Category: Dutton, P L]]
+
[[Category: Dutton PL]]
-
[[Category: Ermler, U]]
+
[[Category: Ermler U]]
-
[[Category: Page, C C]]
+
[[Category: Page CC]]
-
[[Category: Unciuleac, M]]
+
[[Category: Unciuleac M]]
-
[[Category: Warkentin, E]]
+
[[Category: Warkentin E]]
-
[[Category: Dimer heterotrimer]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Xanthine oxidase family]]
+

Current revision

Structure of 4-hydroxybenzoyl-CoA reductase from Thauera aromatica

PDB ID 1rm6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rm6"
Personal tools