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1s20

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Current revision (06:11, 23 August 2023) (edit) (undo)
 
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<StructureSection load='1s20' size='340' side='right'caption='[[1s20]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1s20' size='340' side='right'caption='[[1s20]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1s20]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S20 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1S20 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1s20]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S20 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nxu|1nxu]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s20 OCA], [https://pdbe.org/1s20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s20 RCSB], [https://www.ebi.ac.uk/pdbsum/1s20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s20 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YIAK, B3575 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1s20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s20 OCA], [http://pdbe.org/1s20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1s20 RCSB], [http://www.ebi.ac.uk/pdbsum/1s20 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1s20 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DLGD_ECOLI DLGD_ECOLI]] Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.<ref>PMID:11741871</ref>
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[https://www.uniprot.org/uniprot/DLGD_ECOLI DLGD_ECOLI] Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.<ref>PMID:11741871</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Acton, T B]]
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[[Category: Acton TB]]
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[[Category: Benach, J]]
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[[Category: Benach J]]
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[[Category: Forouhar, F]]
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[[Category: Forouhar F]]
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[[Category: Kulkarni, K]]
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[[Category: Kulkarni K]]
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[[Category: Lee, I]]
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[[Category: Lee I]]
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[[Category: Montelione, G T]]
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[[Category: Montelione GT]]
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[[Category: Structural genomic]]
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[[Category: Tong L]]
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[[Category: Tong, L]]
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[[Category: Xiao R]]
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[[Category: Xiao, R]]
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[[Category: Alpha beta dimeric protein]]
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[[Category: Nesg]]
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[[Category: Oxidoreductase]]
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[[Category: PSI, Protein structure initiative]]
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Current revision

A novel NAD binding protein revealed by the crystal structure of E. Coli 2,3-diketogulonate reductase (YiaK) NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER82

PDB ID 1s20

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