1u16

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Current revision (06:36, 23 August 2023) (edit) (undo)
 
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<StructureSection load='1u16' size='340' side='right'caption='[[1u16]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1u16' size='340' side='right'caption='[[1u16]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1u16]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anapl Anapl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U16 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1u16]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anas_platyrhynchos Anas platyrhynchos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U16 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hy0|1hy0]], [[1hy1|1hy1]], [[1u15|1u15]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Argininosuccinate_lyase Argininosuccinate lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.2.1 4.3.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u16 OCA], [https://pdbe.org/1u16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u16 RCSB], [https://www.ebi.ac.uk/pdbsum/1u16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u16 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u16 OCA], [https://pdbe.org/1u16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u16 RCSB], [https://www.ebi.ac.uk/pdbsum/1u16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u16 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ARLY1_ANAPL ARLY1_ANAPL]] Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles. Despite possessing the necessary catalytic residues, this protein does not function as an enzymatically active argininosuccinate lyase.<ref>PMID:7944404</ref>
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[https://www.uniprot.org/uniprot/ARLY1_ANAPL ARLY1_ANAPL] Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles. Despite possessing the necessary catalytic residues, this protein does not function as an enzymatically active argininosuccinate lyase.<ref>PMID:7944404</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anapl]]
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[[Category: Anas platyrhynchos]]
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[[Category: Argininosuccinate lyase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Creagh, L]]
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[[Category: Creagh L]]
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[[Category: Greene, C]]
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[[Category: Greene C]]
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[[Category: Haynes, C]]
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[[Category: Haynes C]]
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[[Category: Howell, P L]]
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[[Category: Howell PL]]
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[[Category: Sampaleanu, L M]]
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[[Category: Sampaleanu LM]]
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[[Category: Tsai, M]]
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[[Category: Tsai M]]
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[[Category: Duck-delta-crystallin]]
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[[Category: Enzyme mechanism]]
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[[Category: Eye lens protein]]
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[[Category: Lyase]]
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Current revision

Crystal structure of a duck-delta-crystallin-1 double loop mutant (DLM) in complex with sulfate

PDB ID 1u16

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