1u18
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='1u18' size='340' side='right'caption='[[1u18]], [[Resolution|resolution]] 1.96Å' scene=''> | <StructureSection load='1u18' size='340' side='right'caption='[[1u18]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1u18]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1u18]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U18 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=HSM:HISTAMINE'>HSM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=HSM:HISTAMINE'>HSM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u18 OCA], [https://pdbe.org/1u18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u18 RCSB], [https://www.ebi.ac.uk/pdbsum/1u18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u18 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u18 OCA], [https://pdbe.org/1u18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u18 RCSB], [https://www.ebi.ac.uk/pdbsum/1u18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u18 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NP1_RHOPR NP1_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 26: | Line 26: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Rhodnius prolixus]] |
| - | [[Category: Goodin | + | [[Category: Goodin DB]] |
| - | [[Category: Vetter | + | [[Category: Vetter SW]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 06:36, 23 August 2023
1.96 A Crystal structure of H60C mutant of nitrophorin complexed with histamine
| |||||||||||
