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1xhc
From Proteopedia
(Difference between revisions)
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<StructureSection load='1xhc' size='340' side='right'caption='[[1xhc]], [[Resolution|resolution]] 2.35Å' scene=''> | <StructureSection load='1xhc' size='340' side='right'caption='[[1xhc]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1xhc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1xhc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XHC FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xhc OCA], [https://pdbe.org/1xhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xhc RCSB], [https://www.ebi.ac.uk/pdbsum/1xhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xhc ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xhc OCA], [https://pdbe.org/1xhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xhc RCSB], [https://www.ebi.ac.uk/pdbsum/1xhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xhc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NROR_PYRFU NROR_PYRFU] Catalyzes the NADH-dependent reduction of rubredoxin (Rd), a small iron-containing redox protein (PubMed:10464233, PubMed:11398485, PubMed:15746356). Can also reduce other electron carriers, including 2,6-dichlorophenol indophenol, benzyl viologen and menadione, but rubredoxin is the most efficient electron acceptor (PubMed:10464233, PubMed:11398485, PubMed:15746356). Does not reduce ferredoxin (PubMed:10464233). Shows comparable activity with NADPH and NADH as electron donors, but NADPH is probably the preferred physiological electron donor (PubMed:10464233, PubMed:11398485). Is probably part of an oxygen detoxification system that protects P.furiosus during exposure to oxygen (PubMed:15746356).<ref>PMID:10464233</ref> <ref>PMID:11398485</ref> <ref>PMID:15746356</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xhc ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xhc ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Pyrococcus furiosus DSM 3638]] |
| - | [[Category: Adams | + | [[Category: Adams MWW]] |
| - | [[Category: | + | [[Category: Arendall III WB]] |
| - | [[Category: | + | [[Category: Brereton PS]] |
| - | [[Category: | + | [[Category: Chen L]] |
| - | + | [[Category: Horanyi P]] | |
| - | [[Category: | + | [[Category: Izumi M]] |
| - | [[Category: Izumi | + | [[Category: Jenney Jr FE]] |
| - | [[Category: Jenney | + | [[Category: Lee D]] |
| - | [[Category: Lee | + | [[Category: Liu Z-J]] |
| - | [[Category: Liu | + | [[Category: Poole II FL]] |
| - | [[Category: | + | [[Category: Richardson DC]] |
| - | [[Category: Richardson | + | [[Category: Richardson JS]] |
| - | [[Category: | + | [[Category: Rose JP]] |
| - | [[Category: | + | [[Category: Shah A]] |
| - | [[Category: Shah | + | [[Category: Shah C]] |
| - | [[Category: Shah | + | [[Category: Sugar FJ]] |
| - | [[Category: Sugar | + | [[Category: Tempel W]] |
| - | [[Category: Tempel | + | [[Category: Wang B-C]] |
| - | [[Category: Wang | + | [[Category: Weinberg MV]] |
| - | [[Category: Weinberg | + | |
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Current revision
NADH oxidase /nitrite reductase from Pyrococcus furiosus Pfu-1140779-001
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Categories: Large Structures | Pyrococcus furiosus DSM 3638 | Adams MWW | Arendall III WB | Brereton PS | Chen L | Horanyi P | Izumi M | Jenney Jr FE | Lee D | Liu Z-J | Poole II FL | Richardson DC | Richardson JS | Rose JP | Shah A | Shah C | Sugar FJ | Tempel W | Wang B-C | Weinberg MV
