1z2u

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Current revision (07:03, 23 August 2023) (edit) (undo)
 
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<StructureSection load='1z2u' size='340' side='right'caption='[[1z2u]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
<StructureSection load='1z2u' size='340' side='right'caption='[[1z2u]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1z2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z2U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1z2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z2U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BU3:(R,R)-2,3-BUTANEDIOL'>BU3</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ubc-2, let-70 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BU3:(R,R)-2,3-BUTANEDIOL'>BU3</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2u OCA], [https://pdbe.org/1z2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z2u RCSB], [https://www.ebi.ac.uk/pdbsum/1z2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z2u ProSAT], [https://www.topsan.org/Proteins/SECSG/1z2u TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2u OCA], [https://pdbe.org/1z2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z2u RCSB], [https://www.ebi.ac.uk/pdbsum/1z2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z2u ProSAT], [https://www.topsan.org/Proteins/SECSG/1z2u TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/UBC2_CAEEL UBC2_CAEEL]] Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.
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[https://www.uniprot.org/uniprot/UBC2_CAEEL UBC2_CAEEL] Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Caeel]]
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[[Category: Caenorhabditis elegans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ubiquitin--protein ligase]]
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[[Category: DiGiamamarino E]]
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[[Category: DiGiamamarino, E]]
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[[Category: Gavira JA]]
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[[Category: Gavira, J A]]
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[[Category: Liu ZJ]]
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[[Category: Liu, Z J]]
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[[Category: Meehan E]]
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[[Category: Meehan, E]]
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[[Category: Ng JD]]
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[[Category: Ng, J D]]
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[[Category: Tempel W]]
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[[Category: Structural genomic]]
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[[Category: Wang BC]]
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[[Category: Tempel, W]]
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[[Category: Wang, B C]]
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[[Category: Caenorhabditis elegan]]
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[[Category: Ligase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Proteosome pathway]]
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[[Category: Secsg]]
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[[Category: Ubiquitin-conjugating enzyme]]
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Current revision

The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance

PDB ID 1z2u

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