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1z4u

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<StructureSection load='1z4u' size='340' side='right'caption='[[1z4u]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1z4u' size='340' side='right'caption='[[1z4u]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1z4u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z4U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1z4u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z4U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH9:(2Z)-2-[(1-ADAMANTYLCARBONYL)AMINO]-3-[4-(2-BROMOPHENOXY)PHENYL]PROP-2-ENOIC+ACID'>PH9</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yvf|1yvf]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH9:(2Z)-2-[(1-ADAMANTYLCARBONYL)AMINO]-3-[4-(2-BROMOPHENOXY)PHENYL]PROP-2-ENOIC+ACID'>PH9</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z4u OCA], [https://pdbe.org/1z4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z4u RCSB], [https://www.ebi.ac.uk/pdbsum/1z4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z4u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z4u OCA], [https://pdbe.org/1z4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z4u RCSB], [https://www.ebi.ac.uk/pdbsum/1z4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z4u ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O93077_9HEPC O93077_9HEPC]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hepacivirus C]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Anstadt R]]
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[[Category: Anstadt, R]]
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[[Category: Finzel BC]]
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[[Category: Finzel, B C]]
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[[Category: Greene M]]
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[[Category: Greene, M]]
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[[Category: Gross RJ]]
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[[Category: Gross, R J]]
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[[Category: Harris MS]]
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[[Category: Harris, M S]]
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[[Category: Mitchell MA]]
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[[Category: Mitchell, M A]]
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[[Category: Nugent R]]
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[[Category: Nugent, R]]
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[[Category: Pfefferkorn JA]]
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[[Category: Pfefferkorn, J A]]
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[[Category: Shelly JA]]
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[[Category: Shelly, J A]]
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[[Category: Wells PA]]
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[[Category: Wells, P A]]
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[[Category: Finger]]
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[[Category: Hcv]]
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[[Category: Ns5b]]
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[[Category: Palm]]
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[[Category: Polymerase]]
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[[Category: Thumb]]
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[[Category: Transferase]]
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Revision as of 07:03, 23 August 2023

hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585

PDB ID 1z4u

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OCA

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