1z6x

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Current revision (07:04, 23 August 2023) (edit) (undo)
 
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<StructureSection load='1z6x' size='340' side='right'caption='[[1z6x]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='1z6x' size='340' side='right'caption='[[1z6x]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1z6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1Z6X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1z6x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z6X FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1z6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z6x OCA], [http://pdbe.org/1z6x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z6x RCSB], [http://www.ebi.ac.uk/pdbsum/1z6x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1z6x ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z6x OCA], [https://pdbe.org/1z6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z6x RCSB], [https://www.ebi.ac.uk/pdbsum/1z6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z6x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ARF4_HUMAN ARF4_HUMAN]] GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
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[https://www.uniprot.org/uniprot/ARF4_HUMAN ARF4_HUMAN] GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C]]
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[[Category: Arrowsmith C]]
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[[Category: Atanassova, A]]
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[[Category: Atanassova A]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Choe, J]]
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[[Category: Choe J]]
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[[Category: Edwards, A]]
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[[Category: Edwards A]]
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[[Category: Park, H]]
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[[Category: Park H]]
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[[Category: Structural genomic]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M]]
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[[Category: Gdp-binding]]
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[[Category: Golgi stack]]
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[[Category: Lipoprotein]]
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[[Category: Membrane trafficking]]
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[[Category: Myristate]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Sgc]]
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[[Category: Transport protein]]
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Current revision

Structure Of Human ADP-Ribosylation Factor 4

PDB ID 1z6x

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