1zxl

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Current revision (07:16, 23 August 2023) (edit) (undo)
 
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<StructureSection load='1zxl' size='340' side='right'caption='[[1zxl]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='1zxl' size='340' side='right'caption='[[1zxl]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zxl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZXL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zxl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZXL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JP1:N-[3-CHLORO-4-(4-CHLORO-2-HYDROXYPHENOXY)PHENYL]MORPHOLINE-4-CARBOXAMIDE'>JP1</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nhd|1nhd]], [[1nhg|1nhg]], [[1nhw|1nhw]], [[1nnu|1nnu]], [[1zw1|1zw1]], [[1zsn|1zsn]], [[1zxb|1zxb]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JP1:N-[3-CHLORO-4-(4-CHLORO-2-HYDROXYPHENOXY)PHENYL]MORPHOLINE-4-CARBOXAMIDE'>JP1</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PfENR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxl OCA], [https://pdbe.org/1zxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zxl RCSB], [https://www.ebi.ac.uk/pdbsum/1zxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zxl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxl OCA], [https://pdbe.org/1zxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zxl RCSB], [https://www.ebi.ac.uk/pdbsum/1zxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zxl ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9BH77_PLAFA Q9BH77_PLAFA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Plafa]]
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[[Category: Plasmodium falciparum]]
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[[Category: Anderson, J W]]
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[[Category: Anderson JW]]
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[[Category: Fidock, D A]]
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[[Category: Fidock DA]]
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[[Category: Freundlich, J S]]
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[[Category: Freundlich JS]]
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[[Category: Jacobs, W R]]
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[[Category: Jacobs Jr WR]]
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[[Category: Jacobus, D P]]
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[[Category: Jacobus DP]]
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[[Category: Kuo, M]]
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[[Category: Kuo M]]
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[[Category: Lucumi, E]]
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[[Category: Lucumi E]]
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[[Category: Sacchettini, J C]]
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[[Category: Sacchettini JC]]
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[[Category: Sarantakis, D]]
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[[Category: Sarantakis D]]
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[[Category: Schiehser, G A]]
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[[Category: Schiehser GA]]
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[[Category: Shieh, H M]]
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[[Category: Shieh HM]]
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[[Category: Yu, M]]
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[[Category: Yu M]]
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[[Category: Oxidoreductase]]
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Current revision

Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives

PDB ID 1zxl

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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