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2a4e

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Current revision (07:18, 23 August 2023) (edit) (undo)
 
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<StructureSection load='2a4e' size='340' side='right'caption='[[2a4e]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='2a4e' size='340' side='right'caption='[[2a4e]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2a4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A4E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2a4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A4E FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zvn|1zvn]], [[1zxk|1zxk]], [[2a4c|2a4c]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cdh11, Cad-11 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a4e OCA], [https://pdbe.org/2a4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a4e RCSB], [https://www.ebi.ac.uk/pdbsum/2a4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a4e ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a4e OCA], [https://pdbe.org/2a4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a4e RCSB], [https://www.ebi.ac.uk/pdbsum/2a4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a4e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CAD11_MOUSE CAD11_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
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[https://www.uniprot.org/uniprot/CAD11_MOUSE CAD11_MOUSE] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Arkus, N]]
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[[Category: Arkus N]]
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[[Category: Bahna, F]]
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[[Category: Bahna F]]
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[[Category: Chen, C P]]
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[[Category: Chen CP]]
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[[Category: Ciatto, C]]
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[[Category: Ciatto C]]
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[[Category: Honig, B]]
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[[Category: Honig B]]
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[[Category: Jessell, T M]]
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[[Category: Jessell TM]]
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[[Category: Patel, S D]]
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[[Category: Patel SD]]
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[[Category: Price, S R]]
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[[Category: Price SR]]
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[[Category: Rajebhosale, M]]
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[[Category: Rajebhosale M]]
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[[Category: Shapiro, L]]
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[[Category: Shapiro L]]
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[[Category: Cadherin]]
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[[Category: Calcium binding]]
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[[Category: Cell adhesion]]
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[[Category: Dimer]]
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Current revision

Crystal structure of mouse cadherin-11 EC1-2

PDB ID 2a4e

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